WHO: First Zika vaccine trials may come too late for Brazil

The first tests of Zika vaccines on humans are expected to start only at the end of the year and will therefore not be able to help fight the current outbreak in Brazil, a senior World Health Organization (WHO) official said Wednesday.

The UN health agency had convened international experts this week in Geneva to discuss strategies to develop the right vaccine and diagnostic tools, as well as methods to fight mosquitoes.

WHO has made it an urgent task to drive this research forward because of strong indications that the virus causes neurological defects in unborn babies.

There are currently 18 research projects on vaccines against the virus, which usually causes only mild flu symptoms.

The most advanced of them are "still a few months away from first human clinical trials," said Marie-Paule Kieny, WHO's chief innovation officer.

"They might come too late for the current outbreak in Brazil," she added.

Brazil has had the largest share of infections amid the outbreak in Latin America. Brazilian authorities have estimated up to 1.5 million infections, but they have stopped counting due to the rapid spread of the virus.

The virus is mostly transmitted by Aedes aegypti mosquitoes, which also spread very similar viruses including the one that causes dengue fever.

However, insecticides have not had a significant impact on dengue transmission and might therefore also not help against Zika, WHO cautioned.

"Aedes aegypti is the cockroach of mosquitoes," Kieny said.

Latin American countries are considering alternative techniques, such as sterilizing insects in laboratories, infecting them with certain bacteria, or using genetic engineering.

"Extreme rigour" was needed for evaluating such novel tools, WHO said.

Developing a medicine against Zika is not a priority because it would be difficult to test new products on pregnant women, according to WHO.

Last update: Wed, 09/03/2016 - 17:07


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